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Year | Number of Results |
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2009 | 1 |
2010 | 2 |
2012 | 1 |
2015 | 1 |
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2020 | 1 |
2024 | 0 |
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Page 1
Active-site gating regulates substrate selectivity in a chymotrypsin-like serine protease the structure of haemophilus influenzae immunoglobulin A1 protease.
J Mol Biol. 2009 Jun 12;389(3):559-74. doi: 10.1016/j.jmb.2009.04.041. Epub 2009 Apr 23.
J Mol Biol. 2009.
PMID: 19393662
Free PMC article.
Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties.
Soth MJ, Le K, Di Francesco ME, Hamilton MM, Liu G, Burke JP, Carroll CL, Kovacs JJ, Bardenhagen JP, Bristow CA, Cardozo M, Czako B, de Stanchina E, Feng N, Garvey JR, Gay JP, Do MKG, Greer J, Han M, Harris A, Herrera Z, Huang S, Giuliani V, Jiang Y, Johnson SB, Johnson TA, Kang Z, Leonard PG, Liu Z, McAfoos T, Miller M, Morlacchi P, Mullinax RA, Palmer WS, Pang J, Rogers N, Rudin CM, Shepard HE, Spencer ND, Theroff J, Wu Q, Xu A, Yau JA, Draetta G, Toniatti C, Heffernan TP, Jones P.
Soth MJ, et al. Among authors: johnson ta.
J Med Chem. 2020 Nov 12;63(21):12957-12977. doi: 10.1021/acs.jmedchem.0c01398. Epub 2020 Oct 29.
J Med Chem. 2020.
PMID: 33118821
Free PMC article.
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The Ω-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function.
Johnson TA, Holyoak T.
Johnson TA, et al.
Biochemistry. 2012 Nov 27;51(47):9547-59. doi: 10.1021/bi301278t. Epub 2012 Nov 14.
Biochemistry. 2012.
PMID: 23127136
Free PMC article.
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A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin.
Davlieva M, Shi Y, Leonard PG, Johnson TA, Zianni MR, Arias CA, Ladbury JE, Shamoo Y.
Davlieva M, et al. Among authors: johnson ta.
Nucleic Acids Res. 2015 May 19;43(9):4758-73. doi: 10.1093/nar/gkv321. Epub 2015 Apr 19.
Nucleic Acids Res. 2015.
PMID: 25897118
Free PMC article.
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Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase.
Johnson TA, Mcleod MJ, Holyoak T.
Johnson TA, et al.
Biochemistry. 2016 Jan 26;55(3):575-87. doi: 10.1021/acs.biochem.5b01215. Epub 2016 Jan 13.
Biochemistry. 2016.
PMID: 26709450
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Increasing the conformational entropy of the Omega-loop lid domain in phosphoenolpyruvate carboxykinase impairs catalysis and decreases catalytic fidelity.
Johnson TA, Holyoak T.
Johnson TA, et al.
Biochemistry. 2010 Jun 29;49(25):5176-87. doi: 10.1021/bi100399e.
Biochemistry. 2010.
PMID: 20476774
Free PMC article.
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The pyruvate kinase model system, a cautionary tale for the use of osmolyte perturbations to support conformational equilibria in allostery.
Fenton AW, Johnson TA, Holyoak T.
Fenton AW, et al. Among authors: johnson ta.
Protein Sci. 2010 Sep;19(9):1796-800. doi: 10.1002/pro.450.
Protein Sci. 2010.
PMID: 20629175
Free PMC article.
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